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Supplements28 mentions

L-Tyrosine

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Use L-tyrosine as a dopamine precursor to support working memory and mental performance, especially under stress or cognitive load. The protocol emphasized starting with a minimal effective dose rather than the very high study dose discussed, with a practical example around 250 mg, because the goal is to nudge catecholamine availability without overdoing it.

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But nonetheless, taking L-tyrosine will lead to fairly substantial increases in dopamine within about 15 to 45 minutes. And it lasts for about 30 minutes to two hours and then there's kind of a tapering off.

Andrew Huberman · Control Your Brain Chemistry for Focus, Motivation & Well-Being | Huberman Lab Essentials · Aug 6, 2026 · 14:05 · YouTube ↗
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