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Supplements10 mentions

A potent glucose-lowering supplement used with doses explored around 0.5–1.5 g per day. It’s often discussed as having effects comparable to medications like metformin or glibenclamide, so it should be treated seriously and used with medical guidance. The main appeal is its ability to improve blood sugar control through a strong metabolic effect.

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I don't usually give berberine long term, but it definitely short term, you can use it as pulse treatment for these patients.

huberman · Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi · Nov 24, 2025 · 1:13:18 · open ↗
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