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Supplements33 mentions

L-Theanine

A calming amino acid commonly paired with caffeine to smooth out jitters while preserving alertness. Typical doses mentioned are about 100 mg, with more effective ranges around 200–400 mg and up to 900 mg/day reported as generally safe, though higher amounts may cause sleepiness. It’s also used 30–60 minutes before bed as part of a sleep stack to promote relaxation and easier sleep onset.

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“But theanine, which typically is taken in dosages anywhere from 100 milligrams to 400 milligrams, theanine can be great for many people, but for people who have excessively vivid dreams those excessively vivid dreams can lead to immediate waking and sometimes a little bit of anxiety upon waking in the middle of the night. So some people who wake up in the middle of the night so jolted mentally and physically out of sleep because of their intense dreams would do well to avoid theanine supplementation.”

Andrew Huberman · Essentials: Developing a Rational Approach to Supplementation for Health & Performance · Oct 22, 2026 · 9:47 · YouTube ↗
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