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Supplements2 mentions

5-Methyltetrahydrofolate

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This is the use of 5-MTHF/methylfolate as a targeted folate form to reduce elevated homocysteine. The idea is that supporting the remethylation of homocysteine to methionine can help raise endogenous SAMe and may improve nitric-oxide-related vascular function by bringing homocysteine down.

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Oh, I do take methylfolate and methyl B12. And again, the rationale there is I do think there's some evidence that elevated levels of homocysteine are bad in and of themselves.

huberman · Supplements for Longevity & Their Efficacy | Dr. Peter Attia · Jul 29, 2024 · 2:14:03 · open ↗
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