A 50 mg apigenin supplement, typically taken in the evening, derived from chamomile. It’s used to promote sleepiness and help with both falling asleep and staying asleep, likely through its calming effects. One caveat is that it can act as a fairly potent estrogen inhibitor, so people who want to keep estrogen levels high may want to avoid it.
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“50, 5-0 milligrams of apigenin. And again, you could just take the apigenin on its own.”
huberman · Essentials: Sleep Toolkit for Optimizing Sleep & Sleep-Wake Timing · Jun 11, 2026 · 27:00 · open ↗