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Supplements2 mentions

Supplement choline to bring total daily intake into the 500 mg to 1 g range, with some people using smaller doses like 50–100 mg to top up toward 1 g or even 2 g per day. The goal is to support adequate choline status for functions like acetylcholine production, liver health, and overall methylation and membrane maintenance.

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In general, most people should probably strive to get somewhere between 500 milligrams and a gram of choline per day, so 1,000 milligrams.

huberman · Food & Supplements for Brain Health & Cognitive Performance | Huberman Lab Essentials · Sep 11, 2025 · 6:38 · open ↗
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