A practical form of calorie restriction that reduces total intake by skipping one meal each day, often breakfast or dinner, to lengthen the overnight fast. The goal is to create a sustained energy deficit that may support longevity and metabolic health, while still being done in a controlled, tolerable way.
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“Overall, from these animal studies, clearly benefits from reducing calorie intake.”
huberman · Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray · Feb 23, 2026 · 1:15:37 · open ↗