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Supplements2 mentions

An intermittent rapamycin protocol used as a geroprotective intervention, commonly taken at 8 mg once per week rather than daily. One described pattern is about two months on followed by one month off to reduce aphthous ulcers/canker sores. The appeal is its reputation as a strong longevity-focused molecule, with the dosing schedule aimed at preserving the anti-aging signal while improving tolerability.

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I take eight milligrams once a week for as long as I can tolerate it, but I usually have to take breaks.

huberman · Supplements for Longevity & Their Efficacy | Dr. Peter Attia · Jul 29, 2024 · 18:16 · open ↗
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