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Topical Caffeine
Shop on AmazonA caffeine ointment or cream is applied directly to the scalp, typically about three times per week. The idea is to inhibit PDE and support hair follicles by indirectly boosting IGF-1 and reducing apoptosis in the stem-cell niche, helping maintain hair growth.
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“Caffeine is actually another one. Wait, you have to explain how this works. How do people get caffeine into the hair follicle? Topically, the caffeine enters the scalp and crowds out, like somewhat crowds out the androgen.”
Andrew Huberman · Essentials: Tools for Hormone Optimization in Males | Dr. Kyle Gillett · Jul 2, 2026 · 34:48 · YouTube ↗
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