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Topical Caffeine
Shop on AmazonA caffeine ointment or cream is applied directly to the scalp, typically about three times per week. The idea is to inhibit PDE and support hair follicles by indirectly boosting IGF-1 and reducing apoptosis in the stem-cell niche, helping maintain hair growth.
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“By ingesting caffeine or by applying topical caffeine ointment or cream to the scalp, you can suppress PDE sufficiently enough to increase IGF-1 and increase some hair growth or at least maintain hair growth in that region. Head-to-head topical caffeine application can be as effective as minoxidil application without actually lowering things like blood pressure and potentially increasing prolactin.”
huberman · The Science of Healthy Hair, Hair Loss and How to Regrow Hair · Apr 10, 2023 · 1:16:32 · open ↗
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