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Supplements3 mentions

A supervised psychotherapy protocol using MDMA to help treat post-traumatic stress disorder. Typical clinical dosing is about 0.75 to 1.5 mg/kg, and some protocols use an initial dose followed by a half-dose booster 90 minutes to 2.5 hours later. The goal is to reduce fear and defensiveness during therapy, making traumatic material easier to process and integrate.

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I think the standard MAPS dose is 150 to 175 milligrams. Again, doing this with a physician, et cetera, controlled clinical trial, legal.

huberman · Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams · Jun 4, 2026 · 17:21 · open ↗
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