Avoid Cannabis When Psychosis Risk Is Elevated

This recommendation is to avoid cannabis use in people who have schizophrenia or who are at elevated risk for psychotic disorders, especially if they have a first-degree relative with schizophrenia or psychotic bipolar disorder. The rationale is that cannabis can worsen or trigger psychotic symptoms such as hallucinations, delusions, and psychotic episodes, increasing the chance of symptom flare-ups in vulnerable people.