Supplements1 mentions

Agmatine

Agmatine has shown notable effects on several types of pain, including osteoarthritis and injury-related pain, and has been studied for lumbar disc-associated radiculopathy. Use study-specific dosage regimens rather than taking it arbitrarily.

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“I'd be remiss if I didn't mention the two that I get asked most often about, which are agmatine and S-adenosylmethionine, which is sometimes called SAMe. Both of those have been shown to have some impact categorized on examine as notable impact on various forms of pain due to osteoarthritis or due to injury of various kinds.”

huberman · How to Control Your Sense of Pain & Pleasure · Aug 9, 2021 · 1:12:35 · open ↗

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