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Artificial Sweeteners (Aspartame, Sucralose, Saccharin)

Aspartame, sucralose, and saccharin were discussed as having broadly similar effects: they may cause transient increases and then decreases in blood glucose and can increase hunger in some people. In moderation they probably do not meaningfully break a fast, but excess may negatively affect the gut microbiome.

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“There is evidence that when people ingest artificial sweeteners, that it can create a transient increase in blood glucose, followed by a transient decrease in blood glucose below baseline... Aspartame and sucralose, saccharin, I think we can say, more or less the same.”

huberman · Effects of Fasting & Time Restricted Eating on Fat Loss & Health | Huberman Lab Podcast #41 · Oct 11, 2021 · 1:59:09 · open ↗

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