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Supplements1 mentions

Kava may help reduce anxiety, with studies using roughly 100 mg of extract in some cases and active kavalactones around 150 mg, with a broader studied range of 50–300 mg. Effects were seen after about 3 weeks; no hepatotoxic signals were reported in the studies reviewed, but it is still advisable to check with a doctor.

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The last compound I want to mention is... kava. Kava has been shown in eight studies to have a very potent effect on reducing anxiety... after a period of about three weeks of treatment with anywhere from 150 milligrams of what are called active kava lactones.

huberman · Erasing Fears & Traumas Based on the Modern Neuroscience of Fear · Dec 6, 2021 · 2:06:36 · open ↗
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