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Use Pre-Fatigue
For hypertrophy, pre-fatigue a target muscle with an isolation exercise before compound work if you want to guarantee that muscle gets emphasized.
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“You can do this thing called pre-fatigue. [00:30:02] So say you're going to do a back day. [00:30:04] You could go in and do nothing but isolated biceps as your very first exercise”
Andrew Huberman · Essentials: Optimal Protocols to Build Strength & Grow Muscles | Dr. Andy Galpin · Sep 24, 2026 · 27:45 · YouTube ↗
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