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Finasteride

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Potent 5-alpha reductase inhibitor used to reduce DHT, increase hair count, reduce hair loss, and increase hair thickness. Oral starting range suggested as 0.5 mg to 1 mg per day; host emphasizes starting low, waiting a long time before increasing, and considering up to 25 weeks before dose escalation. Effective blood level may be around 0.2 mg. Topical option discussed as 1 mL of 0.25% once per week as a practical starting regimen. Side effects can include reduced libido, reduced sexual function, reduced drive/motivation, depressive symptoms, and possible post-finasteride syndrome.

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Some recommendations that I was able to arrive at based on the clinical studies and frankly, in discussion with some doctors who prescribe finasteride were the following, 0.5 milligrams to one milligram of finasteride as a tablet per day seems to be an effective and pretty safe starting place for most people.

huberman · The Science of Healthy Hair, Hair Loss and How to Regrow Hair · Apr 10, 2023 · 1:47:25 · open ↗
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