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Supplements1 mentions

Needed along with estrogen replacement to avoid unopposed estrogen and increased endometrial cancer risk; can be taken daily or cyclically.

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And you can't have unopposed estrogen without reaching the risk of endometrial cancer. And so that's why we need to have some progestin.

huberman · Female Hormone Health, Fertility & Vitality | Dr. Natalie Crawford · Nov 13, 2023 · 3:20:59 · open ↗
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