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Methadone
Medication option mentioned for treating opioid addiction; described as restoring homeostasis by placing weight on the pleasure side of the balance and having a long enough half-life to avoid the cycle of accumulating 'gremlins.'
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“The other way to restore homeostasis is to give folks a medication that we can actually put on the pleasure side of the balance that has a long enough half-life that it doesn't induce this sort of cycle of accumulating these gremlins. And that's things like buprenorphine or methadone to treat opioid addiction.”
Andrew Huberman · Overcome Addictions and Obsessions of All Kinds | Dr. Anna Lembke · Nov 9, 2026 · 15:46 · YouTube ↗
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