All protocols

During the difficult phase of a lift, try to move the weight as fast as possible while maintaining control; control the easier phase. Do not intentionally slow down either phase for hypertrophy or strength purposes.

Keep range of motion, tempo, and exercise execution consistent so progress in load or reps is meaningful.

If strength or hypertrophy is the goal, perform resistance training before endurance work. If possible, separate endurance and resistance sessions by at least several hours, and avoid doing sprints before leg workouts.

If you prefer activities like tennis, bike rides, hikes, or pickleball, use those for cardiovascular fitness rather than forcing formal cardio sessions.

For reducing body fat or fat loss, prioritize changing nutrition rather than relying on added cardio, Pilates, or ab work alone; nutrition changes are described as the more effective and efficient lever.

There is no danger from training after getting 1–2 fewer hours of sleep than usual; performance may feel worse subjectively, but doing the workout is generally fine.

Use group fitness as an entry point into the gym; it provides social support, scheduled commitment, and exposure to movement patterns.

Before really long-form endurance training, it is probably wise to eat something beforehand to fuel the session.

A meal like oats eaten immediately before a resistance workout likely will not be digested quickly enough to serve as fuel for that session, so pre-workout meal timing matters.

Creatine can raise creatinine on blood tests; inform your physician so the lab result is interpreted correctly.

Some people should avoid evening training because it can disrupt sleep.

May improve energy and productivity for the rest of the day for some people. If switching from afternoon/evening to morning training, expect an initial performance dip that should resolve within a couple weeks.

Incorporate balance work into resistance training to help reduce fall risk and improve the ability to catch yourself. This can be done through unilateral exercises or movements like walking lunges.

If the goal is to hypertrophy the rectus abdominis, train it like any other muscle group with progressive loading rather than endless crunches.

Trains glute and hamstring on one side and can include a balance component. Use external support if needed for stability.

Place a barbell pad on a low bar in a squat rack to support the top of the rear foot more comfortably than a bench during split-stance work.

Suggested as a way to reduce excessive iron load; also framed as helpful because blood banks and hospitals need blood.

Strong caution against getting injections of cells or other unproven interventions, especially from loosely regulated clinics; emphasized need for rigorous testing and trusted clinical oversight. Only use interventions prescribed by a clinician you trust.

Guest says he has a vegetable garden and lots of fruit trees and tries to get food from his own garden; framed as a cleaner food source, though acknowledged as a luxury for many.

Host says he spends extra money on organic produce, while noting the evidence for major differences between organic and non-organic is mixed.

Presented as an ideal approach for cleaner produce.

Guest says he has tried Walter Longo's diet a few times; described as a five-day low-calorie fasting-mimicking protocol lowering intake to about 1,000 calories per day, then returning to normal eating, with a shift toward fat burning.

Optional addition during 3-4 day medically supervised fasts; mentioned alongside water and electrolytes.

Host says he generally has caffeine, electrolytes, and water until about 10 or 11 a.m.

Host suggests finding cognitively challenging activities you want to do enough to choose them voluntarily; examples given include learning a new language or a new instrument.

Host says data show handwriting is very important for development of certain brain circuits, especially relevant for younger people.

Host says he makes it a point to read at least one page and ideally one chapter of a book every day, with his phone out of the room while reading.

Emphasizes that you can eat many different foods, but should not eat only one food; indulgent foods like French fries or burgers are framed as acceptable in moderation.

Wearable device used to measure steps and sleep; guest says they find it useful.

Guest says he measures his steps and finds it useful.