Supplements

Low-dose adjunct medications often prescribed alongside SSRIs for some OCD patients when first-line treatment is insufficient; also referred to here as antipsychotics. Haloperidol was given as an example, with the caveat that dopamine-reducing drugs can have motor side effects.

Mentioned as an OCD medication; noted to be less selective and able to affect neurotransmitter systems beyond serotonin, including epinephrine.

Foundational health support; obtain sufficient essential fatty acids either from food sources or supplements. Fish oil can be taken in liquid or capsule form.

100 mg every third or fourth night, in addition to the standard sleep stack, to enhance ability to get into sleep. Not recommended every night, because taking it too often seems to make the overall sleep stack less effective for him.

Antipsychotic sometimes prescribed as a sedative to allow sleep during manic episodes; requires careful monitoring because of side effects related to white blood cells.

May be prescribed to help induce sleep during manic episodes by reducing neuronal excitability through the GABA system.

Used only when estradiol gets too high; Attia says it must be real microdoses, compounded at 0.1 mg, perhaps 0.1 mg two to three times per week. He aims for estradiol roughly 30–50 and avoids suppressing below 25. Also referred to as Arimidex/Aromidex.

Attia uses injectable testosterone cypionate for TRT, usually at low physiologic doses; typically not more than 100 mg/week. He prefers splitting dosing twice weekly rather than large infrequent doses, and uses subcutaneous rather than intramuscular injection.

Liver-specific cholesterol synthesis inhibitor; Attia uses it especially when statins cause adverse effects.

Protein supplement taken after high-intensity resistance training; mentioned as a protein drink, with protein-containing food as an alternative.

Do not use CBD during pregnancy or while lactating/breastfeeding; includes smoked or edible forms. He explicitly includes CBD in the warning because cannabinoid exposure can interfere with endogenous cannabinoid signaling important for fetal development.

Palmer says he would specifically avoid trazodone in this context because it is an antidepressant and the patient is already hypomanic, so he does not want to push that further.

Mentioned among prescription sleep medicines Palmer may use short-term as a stopgap for keto-related hypomania or insomnia.

For selected patients without a history of addiction, short-term Ativan may be used to restore sleep and help break hypomania. Ativan is often preferred because it is shorter-acting.

Palmer says he may use something like Klonopin short-term to restore sleep and break hypomania in selected patients without addiction history.

Tablet form of caffeine can be used when pairing caffeine with another beverage; one example given was 125–150 mg with herbal tea to build a preference for the tea.

Mentioned as the garlic compound that can help decrease conversion of carnitine/choline to TMAO.

Mentioned as a better way than nicotine to optimize nicotinic receptor activity.

A non-animal whey-like protein made from yeast is described as a promising vegan option with whey-like quality.

Meta-analysis cited suggesting reduced fatigue, increased time to fatigue, and possible small recovery benefits.

Different forms of carnitine are said to have recovery benefits; carnitine tartrate specifically was noted to increase androgen receptor density in muscle cells.

500–1,500 mg per day as an adaptogen; he later specifically suggests adding 1,000 mg/day if needed after starting with ashwagandha; may help buffer stress by reducing cortisol and inflammatory cytokines; if taken daily, cycle off after about 30 days.

Use as foundational insurance against dietary deficiencies, especially if highly active or doing intermittent fasting; take with food and ideally early in the day; avoid exceedingly high doses.

If budget allows, prioritize a broad-spectrum foundational supplement covering vitamins, minerals, adaptogens, probiotics, prebiotics, and digestive enzymes before targeted sleep, focus, or hormone supplements.

Also called rauwolscine; potent stimulant often used for alertness and fat loss. Can be precarious and may cause anxiety, especially on an empty stomach or during subcaloric dieting.

Mentioned as a protein supplement option for reaching protein thresholds; includes milk-protein-based options such as casein.

Mentioned as a protein supplement option for reaching protein thresholds.

Mentioned as a protein supplement option for reaching protein thresholds; potato protein was noted as a potentially strong plant-based substitute for whey.

Classic psychedelic discussed as reliably producing strong effects at 100 micrograms. Context includes legality, safety, guidance, and psychiatric-risk caveats.

Injected into muscles of the forehead, temples, jaw, or neck to provide long-lasting relief of tension-type headaches by blocking neuromuscular signaling; effects can last weeks to months and may require periodic re-ups.