Behaviors

Avoid getting hit in the head; traumatic brain injury is described as a major risk factor for cognitive decline/Alzheimer's.

Described as powerful for memory updating and reframing traumatic experiences through shared narratives and social interaction.

Start very low and go slowly with semaglutide or tirzepatide rather than using conventional doses; intended to reduce excessive weight loss, muscle loss, and nausea.

During GLP-1 use, aim for losing less than or equal to 2 pounds per week to reduce muscle loss.

Repeatedly emphasized as foundational before considering more aggressive interventions like testosterone; includes eating mostly non-processed foods.

Compounded combination intended to address muscle loss associated with tirzepatide by stimulating growth hormone release with sermorelin.

Protocol given for pentadeca-arginate: 500 micrograms injected daily on weekdays with weekends off.

He stated he does not like testosterone pellets or pellet therapy because they expose people to hormone concentrations not seen in nature.

Timing recommendation for ipamorelin: pre-sleep/bedtime.

For bedtime use of ipamorelin and similar peptides, avoid carbohydrates in the prior 45 minutes; Huberman also mentions prior 2 hours, but guest confirms 45 minutes technically.

Recommended specifically for people trying to put on size or get stronger because it increases appetite.

Rather than using one peptide at a time, combine peptides synergistically, sometimes at lower doses, often in one compounded shot.

Example stack of BPC, ipamorelin, and tesamorelin was taken at bedtime.

Recommended schedule derived from traditional growth hormone dosing; also aligned with his general preference for taking breaks from compounds.

200 milligrams per day in the morning.

He reports bedtime use woke him from sleep with hunger and ruined sleep.

Timing recommendation for hexarelin: morning use for clean energy/endurance support.

Preferred timing is morning; also suggested as an option at 3 PM instead of reaching for coffee or a donut during an afternoon slump.

Recommended at bedtime to help settle the nervous system and support sleep; starting dose 3-5 grams at bedtime, and if no effect after a few nights, increase to 10 grams. Also recommended as part of liver mitigation strategies because it supports phase 2 liver detoxification. Pinealon was mentioned as something he likes combining with glycine for sleep support.

Timing recommendation for methylene blue: morning, because it is a cognitive stimulant.

His personal frequency recommendation/preference; notes some people may need it more often.

Recommended initial protocol for IV NAD.

After loading dose, average maintenance recommendation is once per month.

Protocol for subcutaneous NAD: 100 milligrams subcutaneously, five days on and two days off.

If using reverse osmosis, add minerals back because the process also removes key minerals from water.

If using a home reverse osmosis system, fill glass or stainless steel bottles with that water and take them when leaving the house.

Avoid drinking hot liquids from paper cups because the lining can leach BPA, BPS, microplastics, and nanoplastics, especially with hot liquids.

If forced to buy coffee in a paper cup, pour it into a ceramic mug as soon as possible.

Reduce frequency of drinking hot liquids through plastic lids on takeaway cups.

Bring a reusable mug when buying coffee to avoid paper cups and plastic lids; use ceramic, stainless steel, or another vessel that does not contain BPA or BPS. Some places may also offer a discount.